Cross-linked informofers

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Cross-linked informofers.

The proteins of 30S RNP particles containing pre-mRNA (hnRNA) were cross-linked with bifunctional reagents (dimethyl-suberimidate and dimethyl-3,3'-dithiobispropionimidate). Further treatment with 1 or 2 M NaCl dissociates all RNA from protein. However, a significant part of protein particles--informofers being cross-linked survived high salt treatment. Their sedimentation coefficients were clo...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 1979

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/7.6.1649